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The Fondation Brocher is an essential player in this vital thinking process: one which will help make us aware of the real challenges in using our resources for maximum impact on the health of the people of the world.



Professor Daniel Wikler, Harvard University


The Brocher Foundation is a Swiss non-profit private foundation  recognized of public interest. Your donations are tax deductible according to the regulations in force.


December 15 - 16, 2020

Gene drive-based malaria control


Gene drives offer a double-edged alternative to traditional methods of controlling malaria and other vector borne diseases. The appeal of gene drives rests on their extraordinary efficiency in suppressing vector populations and spreading alterations to diminish the ability to host plasmodium.  Concerns over gene drives center on their potential for unlimited spread across borders with uncontrolled effects on the global genetic commons.  Localization safeguards offer a possible escape from this dilemma.   The proposed workshop will bring togethergene drive researchers, developers, regulators, and stakeholders to anticipate data needs and testing methods for gene drives localization safeguards.

While the global debate over the potential benefits and risks of gene drives rests on the assumption of uncontrolled spread, the workshop will specifically review on-going research and development programs that aim to develop mechanisms to control the spread of gene drives through technical safeguards. It will aim to evaluate the ability of these safeguarding design strategies to localize the spread of gene drives and provide recommendations for further research, testing and possible implementation.